The effect of exam stress on serum IL-6, cortisol, CRP and Ige levels

Shamsdin, S.A. and Anvar, M. and Mehrabani, D. (2010) The effect of exam stress on serum IL-6, cortisol, CRP and Ige levels. Iranian Red Crescent Medical Journal, 12 (4). pp. 484-488.

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Abstract

Background: Stress has determining effects on the immune response. This study was undertaken to determine the effect of exam stress on serum IL-6, cortisol, CRP and IgE levels of medical students. Methods: Thirty five university medical students in Southern Iran were enrolled. Two blood samples were provided from each participant one month (first stage) and one hour (second stage) before the exam at 1.00 PM. The students completed the SpielBerger State-Trait Anxiety Inventory (STAI) questionnaire. IL-6, cortisol, CRP and IgE changes were determined in these students. Results: The mean age of the students was 21 years. The exam stress resulted in a significant decrease in the IgE level and a significant increase in the cortisol level. Conclusion: The exam stress can result in a decrease in the IgE level and a significant increase in the cortisol level. So, these changes may indicate the alterations of immunological status and presence of stress in an immunosuppressed individual, affecting his/her health. © Iranian Red Crescent Medical Journal.

Item Type: Article
Additional Information: cited By 3
Uncontrolled Keywords: C reactive protein; hydrocortisone; immunoglobulin E; interleukin 6, adult; article; blood sampling; controlled study; female; human; human experiment; laboratory test; male; medical student; physical examination; protein blood level; State Trait Anxiety Inventory
Divisions: School of Medicine
Depositing User: Unnamed user with email eprints@fums.ac.ir
Date Deposited: 09 Mar 2017 21:18
Last Modified: 09 Mar 2017 21:18
URI: http://eprints.fums.ac.ir/id/eprint/288

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